NUPLAZID Safety Information

Safety Information and possible side effects of NUPLAZID

WHAT IS THE MOST IMPORTANT INFORMATION I SHOULD KNOW ABOUT NUPLAZID?

Warning

WARNING: INCREASED RISK OF DEATH IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS

  • Medicines like NUPLAZID can raise the risk of death in elderly people who have lost touch with reality (psychosis) due to confusion and memory loss (dementia).

  • NUPLAZID is not approved for the treatment of patients with dementia-related psychosis unrelated to the hallucinations and delusions associated with Parkinson’s disease psychosis.

WHO SHOULD NOT TAKE NUPLAZID?

other medications

Do not take NUPLAZID if you have had an allergic reaction to any of the ingredients in NUPLAZID. Allergic reactions have included:

  • Rash

  • Hives

  • Swelling of the tongue, mouth, lips, or face

  • Throat tightness

  • Shortness of breath

 

Do not take NUPLAZID if you have certain heart conditions that change your heart rhythm. It is important to talk to your healthcare provider about this possible side effect. Call your healthcare provider if you feel a change in your heartbeat.

WHAT WARNINGS SHOULD I KNOW ABOUT NUPLAZID?

Warning

NUPLAZID may increase the risk of changes to your heart rhythm. This risk may increase if NUPLAZID is taken with certain other medications known to prolong the QT interval. Tell your healthcare provider about all the medicines you take or have recently taken. 

WHAT MEDICINES MIGHT INTERACT WITH NUPLAZID?

Drug Interactions

Tell your healthcare provider about all the medicines you take. Other medicines may affect how NUPLAZID works. Some medicines should not be taken with NUPLAZID. Your healthcare provider can tell you if it is safe to take NUPLAZID with your other medicines. Do not start or stop any medicines while taking NUPLAZID without talking to your healthcare provider first. 

WHAT ARE THE COMMON SIDE EFFECTS OF NUPLAZID?

possible side effects

The most common side effects of NUPLAZID include swelling in the legs or arms, nausea, confusion, hallucination, constipation, and changes to normal walking. These are not all the possible side effects of NUPLAZID. For more information, ask your healthcare provider about this medicine.

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