How people with Parkinson’s disease describe hallucinations and/or delusions

Seeing things that aren't real

Such as people, either living or deceased, animals, or objects

Hearing things that aren't real

Such as hearing sounds, music, or voices

Paranoia

Such as believing people are talking about you or trying to access your money

False beliefs

Such as fears of your loved ones stealing from you, loved ones putting you in harm's way or being unfaithful

NUPLAZID® (pimavanserin) logo - once daily - 34 mg capsules

Acadia Connect® is a free program that helps people with a NUPLAZID prescription navigate insurance and access resources to start their medication. Learn more and sign up today

Actor portrayals of a man with PD-related hallucinations and delusions walking with his caregiver

Hallucinations and/or delusions related to Parkinson’s-disease are more common than you think, but they're treatable

NUPLAZID® : The only medicine FDA-approved specifically to treat Parkinson's-related hallucinations and/or delusions

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If you are living with Parkinson’s or caring for someone who is, there’s a lot to navigate. New symptoms like Parkinson’s-related hallucinations and/or delusions can add to existing challenges. But NUPLAZID may help manage this aspect of Parkinson’s disease without affecting motor symptoms.

*In the clinical trial, the majority of patients who took NUPLAZID experienced fewer and/or less severe hallucinations and/or delusions associated with Parkinson’s disease psychosis when compared to placebo. NUPLAZID had no effect on motor symptoms compared with a placebo at 6 weeks.

Talk to your doctor about NUPLAZID Why NUPLAZID?
Actor portrayal of a man with pd-related hallucinations and delusions talking with his doctor
"I often prescribe NUPLAZID for patients with Parkinson’s-related hallucinations and delusions because it’s FDA-approved. This reassures both me and my patients."

— Dr. Craig Chepke, MD Dr. Craig Chepke is a paid consultant for Acadia Pharmaceuticals Inc.

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Talking to your doctor about NUPLAZID may help

If you or your loved one is seeing, hearing, or experiencing things that aren't real (hallucinations) and/or believing things that aren't true (delusions), NUPLAZID may help. You can get guidance on what to ask your doctor with this Doctor Discussion Guide.

NUPLAZID is the only medicine approved to treat hallucinations and/or delusions associated with Parkinson’s disease. See what the clinical trial demonstrated about the safety of NUPLAZID and its effect on motor symptoms.

Learn More About NUPLAZID

Parkinson’s-related hallucinations and delusions may be more common than you think—but talking to you doctor may help

Talking to your doctor about new or worsening symptoms like Parkinson’s-related hallucinations and/or delusions can create a lot of confusing emotions, but open conversations can lead to better care. And if you’re experiencing hallucinations and/or delusions, you’re not alone—around 50% of people living with Parkinson's experience them over the course of their disease.

If you’re looking for a way to start this discussion and learn more about hallucinations and/or delusions, download and complete this symptom discussion guide, and bring it to your next doctor’s appointment.

Download Symptom Discussion Guide
Around 50%. Hallucinations and delusions may affect around 50% of people with Parkinson’s over the course of their disease
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Help at every step

Enroll in Acadia Connect® to be paired with a dedicated Care Coordinator who will learn your unique needs. This free program offers personalized support, including insurance navigation and financial assistance options, to help provide service that’s right for you.

Learn More NUPLAZID cost and coverage
IMPORTANT SAFETY INFORMATION and INDICATION
What is the most important information I should know about NUPLAZID?

  • Medicines like NUPLAZID can raise the risk of death in elderly people who have lost touch with reality (psychosis) due to confusion and memory loss (dementia).

  • NUPLAZID is not approved for the treatment of patients with dementia who experience psychosis unless their hallucinations and delusions are related to Parkinson’s disease.

Who should not take NUPLAZID?

  • Do not take NUPLAZID if you have had an allergic reaction to any of the ingredients in NUPLAZID. Allergic reactions have included rash, hives, swelling of the tongue, mouth, lips, or face, throat tightness, and shortness of breath.
  • Do not take NUPLAZID if you have certain heart conditions that change your heart rhythm. It is important to talk to your healthcare provider about this possible side effect. Call your healthcare provider if you feel a change in your heartbeat.

What other warnings should I know about NUPLAZID?

  • QT Interval Prolongation: NUPLAZID may increase the risk of changes to your heart rhythm. This risk may increase if NUPLAZID is taken with certain other medications known to prolong the QT interval. Tell your healthcare provider about all the medicines you take or have recently taken.

    Please also see What is the most important information I should know about NUPLAZID?

What medicine might interact with NUPLAZID?

  • Tell your healthcare provider about all the medicines you take. Other medicines may affect how NUPLAZID works. Some medicines should not be taken with NUPLAZID. Your healthcare provider can tell you if it is safe to take NUPLAZID with your other medicines. Do not start or stop any medicines while taking NUPLAZID without talking to your healthcare provider first.

What are the common side effects of NUPLAZID?

  • The common side effects of NUPLAZID include swelling in the legs or arms, nausea, confusion, hallucination, constipation, and changes to normal walking. These are not all the possible side effects of NUPLAZID. For more information, ask your healthcare provider about this medicine.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088. You can also call Acadia Pharmaceuticals Inc. at 1‑844‑4ACADIA (1‑844‑422‑2342).

Indication

NUPLAZID is a prescription medicine used to treat hallucinations and delusions associated with Parkinson’s disease psychosis.

How should I take NUPLAZID?

The recommended dose of NUPLAZID is one 34 mg capsule once per day, taken by mouth, with or without food.

NUPLAZID is available as 34 mg capsules and 10 mg tablets.

Please read the full Prescribing Information, including Boxed WARNING.