NUPLAZID:
Real help for a real part of Parkinson’s disease

If you’re living with Parkinson’s, you may be among the over 50% of people who will experience hallucinations or delusions over the course of their disease.

NUPLAZID™ (pimavanserin) is the first and only medicine FDA-approved to treat hallucinations and delusions associated with Parkinson’s disease psychosis.

Facts about NUPLAZID

  • clock

    NUPLAZID works around the clock to help reduce Parkinson’s disease hallucinations and delusions

    NUPLAZID works all day and night to help reduce hallucinations and delusions associated with Parkinson’s disease psychosis. You just take two 17‑mg tablets, once a day, at a time that you choose, or as prescribed by your doctor. It’s important to remember that everyone responds to medications differently, so it may take some time for NUPLAZID to start working.

  • chart - downward trend

    NUPLAZID significantly reduced the number and severity of symptoms in the majority of people

    In the clinical trial, the majority of people who took NUPLAZID experienced fewer and/or less severe symptoms. And, after 6 weeks, some people were no longer experiencing any symptoms.

    To test the effectiveness of NUPLAZID, an FDA-accepted tool was used. The tool measures changes in the frequency or severity of hallucinations and delusions in people with Parkinson’s.

    Tell me more about the trial X

    The clinical trial included 199 adults (at least 40 years of age with a mean age of 72 years) diagnosed with Parkinson’s disease psychosis that was severe enough for treatment. It was a randomized, double-blind, placebo-controlled study. Each person was assigned to 1 of 2 groups: those who received NUPLAZID or those who did not. Results were reported after 6 weeks.

  • pills

    Taking NUPLAZID doesn’t require adjusting doses of carbidopa/levodopa

    You can take NUPLAZID without adjusting doses of carbidopa/levodopa medicines. Some medicines should not be taken with NUPLAZID. Tell your doctor about all the medicines you are taking.

  • stop! (hand)

    NUPLAZID has no effect on motor symptoms

    Taking NUPLAZID did not affect motor symptoms in clinical trials.

Back to top
+ Expand - Close

Important Safety Information and Indication for NUPLAZID (pimavanserin) 17-mg Tablets

Elderly people with dementia-related psychosis (having lost touch with reality due to confusion and memory loss) taking antipsychotic drugs are at an increased risk of death. NUPLAZID is not approved for the treatment of patients with dementia-related psychosis unrelated to the hallucinations and delusions associated with Parkinson’s disease psychosis. Continues below

NUPLAZID may cause serious side effects including:

QT Interval Prolongation: NUPLAZID may increase the risk of changes to your heart rhythm. This risk may increase if NUPLAZID is taken with certain other medications known to change heart rhythm. Tell your healthcare provider about all the medicines you take or have recently taken.

It is important to talk to your healthcare provider about the possible side effect of changes to your heart rhythm. Call your healthcare provider right away if you feel a change in your heartbeat.

Do not take NUPLAZID if you have certain kinds of heart conditions such as:

  • An irregular heartbeat
  • A slow heart rate

Before taking NUPLAZID, tell your healthcare provider if you have:

  • Reduced kidney function. NUPLAZID is not recommended if you have severe kidney problems.
  • Reduced liver function. NUPLAZID is not recommended if you have liver problems.

Other medicines may affect how NUPLAZID works. Some medicines should not be taken with NUPLAZID. Your healthcare provider can tell you if it is safe to take NUPLAZID with your other medicines. Do not start or stop any medicines while taking NUPLAZID without talking to your healthcare provider first.

The most common side effects of NUPLAZID include swelling in the legs or arms, nausea, confusion, hallucination, constipation, and changes to normal walking. These are not all the possible side effects of NUPLAZID. For more information, ask your healthcare provider about this medicine.

Tell your healthcare provider if you are pregnant or plan to become pregnant. It is not known if NUPLAZID may harm your unborn baby.

It is not known if NUPLAZID is safe and effective in people under 18 years of age.

Dosage and Administration

The recommended dose of NUPLAZID is 34 mg per day, taken as two 17‑mg tablets, once per day.

Indication

NUPLAZID is a prescription medicine used to treat hallucinations and delusions associated with Parkinson’s disease psychosis.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1‑800‑FDA‑1088. You can also call ACADIA Pharmaceuticals Inc. at 1‑844‑4ACADIA (1‑844‑422‑2342).

Please see full Prescribing Information including Boxed WARNING.

This website is intended for use by US residents.

+ Expand - Close

Important Safety Information and Indication for NUPLAZID (pimavanserin) 17-mg Tablets

Elderly people with dementia-related psychosis (having lost touch with reality due to confusion and memory loss) taking antipsychotic drugs are at an increased risk of death. NUPLAZID is not approved for the treatment of patients with dementia-related psychosis unrelated to the hallucinations and delusions associated with Parkinson’s disease psychosis. Continues below

NUPLAZID may cause serious side effects including:

QT Interval Prolongation: NUPLAZID may increase the risk of changes to your heart rhythm. This risk may increase if NUPLAZID is taken with certain other medications known to change heart rhythm. Tell your healthcare provider about all the medicines you take or have recently taken.

It is important to talk to your healthcare provider about the possible side effect of changes to your heart rhythm. Call your healthcare provider right away if you feel a change in your heartbeat.

Do not take NUPLAZID if you have certain kinds of heart conditions such as:

  • An irregular heartbeat
  • A slow heart rate

Before taking NUPLAZID, tell your healthcare provider if you have:

  • Reduced kidney function. NUPLAZID is not recommended if you have severe kidney problems.
  • Reduced liver function. NUPLAZID is not recommended if you have liver problems.

Other medicines may affect how NUPLAZID works. Some medicines should not be taken with NUPLAZID. Your healthcare provider can tell you if it is safe to take NUPLAZID with your other medicines. Do not start or stop any medicines while taking NUPLAZID without talking to your healthcare provider first.

The most common side effects of NUPLAZID include swelling in the legs or arms, nausea, confusion, hallucination, constipation, and changes to normal walking. These are not all the possible side effects of NUPLAZID. For more information, ask your healthcare provider about this medicine.

Tell your healthcare provider if you are pregnant or plan to become pregnant. It is not known if NUPLAZID may harm your unborn baby.

It is not known if NUPLAZID is safe and effective in people under 18 years of age.

Dosage and Administration

The recommended dose of NUPLAZID is 34 mg per day, taken as two 17‑mg tablets, once per day.

Indication

NUPLAZID is a prescription medicine used to treat hallucinations and delusions associated with Parkinson’s disease psychosis.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1‑800‑FDA‑1088. You can also call ACADIA Pharmaceuticals Inc. at 1‑844‑4ACADIA (1‑844‑422‑2342).

Please see full Prescribing Information including Boxed WARNING.

This website is intended for use by US residents.